Archive for June, 2026

The Hidden Gatekeeper: A Serial Killer Inside the Human Brain

The Hidden Gatekeeperย Best for an engaging, true-crime-style narrative that builds suspense paragraph by paragraph. For over thirty years, neurologists have been tracking a serial killer inside the human brain. We call its wake Alzheimerโ€™s disease. When scientists look at the brains of those affected, they always find the same gruesome crime scene: millions of vital […]

๐—ง๐—ต๐—ฒ ๐—ž๐—ถ๐˜๐—ฐ๐—ต๐—ฒ๐—ป ๐—ฆ๐—ถ๐—ป๐—ธ ๐— ๐—ฒ๐˜๐—ฎ๐—ฝ๐—ต๐—ผ๐—ฟ—Glymphatically Clogged Brains in Alzheimer’s

๐“๐ก๐ž ๐Š๐ข๐ญ๐œ๐ก๐ž๐ง ๐’๐ข๐ง๐ค ๐Œ๐ž๐ญ๐š๐ฉ๐ก๐จ๐ซ–๐๐ž๐ฌ๐ญ ๐Ÿ๐จ๐ซ ๐š ๐›๐ซ๐จ๐š๐ ๐š๐ฎ๐๐ข๐ž๐ง๐œ๐ž ๐ฐ๐ก๐จ ๐ซ๐ž๐ฌ๐ฉ๐จ๐ง๐๐ฌ ๐ฐ๐ž๐ฅ๐ฅ ๐ญ๐จ ๐ฏ๐ข๐ฌ๐ฎ๐š๐ฅ, ๐ž๐ฏ๐ž๐ซ๐ฒ๐๐š๐ฒ ๐š๐ง๐š๐ฅ๐จ๐ ๐ข๐ž๐ฌ. Imagine your brain is a bustling, high-tech city. Every single day, millions of tiny factories (your brain cells) are working hard, creating thoughts and memories. But just like any busy city, this work creates trash. Under normal conditions, your brain […]

The choroid plexus (ChP): hydrodynamic bottleneck and ground zero for Alzheimer’s

The choroid plexus (ChP): hydrodynamic bottleneck and ground zero for Alzheimer’s diseaseย  https://ejournals.uni-muenster.de/fnp/article/view/9368/9664 The Institute has advanced a Dual Sequestration Hypothesis (DSH) related to the protein signatures prevalent in Alzheimer’s disease.ย  If the DSH is correct, the ChP should enlarge and become the sentinel hydrodynamic bottleneck as synthetic particles and their protein sequestrants accumulate. This […]

Book Review: American Traitor by Brad Taylor

ย Mike Guth‘s reviewย  Jun 28, 2026 ย ยท really liked it Book Review: American Traitor (Pike Logan #15) by Brad Taylor Rating: 4 out of 5 Starsย  ย Format: Audiobook Brad Taylorโ€™s American Traitor takes the Pike Logan series to the high-stakes arena of the Asia-Pacific, delivering a tech-heavy, pulse-pounding thriller that manages to be both frighteningly […]

Wasted Economic and Scientific Resources on Targeted Alpha Therapy

๐€๐๐ฏ๐ข๐œ๐ž ๐ญ๐จ ๐š ๐ก๐ž๐š๐ฅ๐ญ๐ก ๐จ๐ฎ๐ญ๐œ๐จ๐ฆ๐ž๐ฌ ๐ซ๐ž๐ฌ๐ž๐š๐ซ๐œ๐ก๐ž๐ซ ๐ฐ๐ก๐จ ๐ก๐š๐ฌ ๐ฐ๐ซ๐ข๐ญ๐ญ๐ž๐ง ๐š๐ง ๐š๐ซ๐ญ๐ข๐œ๐ฅ๐ž ๐ญ๐ก๐š๐ญ ๐œ๐ซ๐ข๐ญ๐ข๐œ๐ข๐ณ๐ž๐ฌ ๐ญ๐ก๐ž ๐จ๐›๐ฏ๐ข๐จ๐ฎ๐ฌ ๐ฌ๐œ๐ข๐ž๐ง๐ญ๐ข๐Ÿ๐ข๐œ ๐š๐ง๐ ๐ž๐œ๐จ๐ง๐จ๐ฆ๐ข๐œ ๐ฐ๐š๐ฌ๐ญ๐ž ๐š๐ฌ๐ฌ๐จ๐œ๐ข๐š๐ญ๐ž๐ ๐ฐ๐ข๐ญ๐ก ๐“๐š๐ซ๐ ๐ž๐ญ๐ž๐ ๐€๐ฅ๐ฉ๐ก๐š ๐“๐ก๐ž๐ซ๐š๐ฉ๐ฒ, ๐š ๐œ๐š๐ง๐œ๐ž๐ซ ๐ญ๐ซ๐ž๐š๐ญ๐ฆ๐ž๐ง๐ญ ๐ญ๐ก๐š๐ญ ๐ข๐ง๐ฏ๐จ๐ฅ๐ฏ๐ž๐ฌ ๐š๐๐ฆ๐ข๐ง๐ข๐ฌ๐ญ๐ž๐ซ๐ข๐ง๐  ๐š ๐ซ๐š๐๐ข๐จ๐š๐œ๐ญ๐ข๐ฏ๐ž ๐๐ซ๐ฎ๐  ๐ญ๐จ ๐š ๐ฏ๐ž๐ซ๐ฒ ๐ฌ๐ข๐œ๐ค ๐ฉ๐š๐ญ๐ข๐ž๐ง๐ญ ๐›๐ฒ ๐ข๐ง๐ญ๐ซ๐š๐ฏ๐ž๐ง๐จ๐ฎ๐ฌ ๐๐ซ๐ข๐ฉ? The scientific argument in the criticism is sound, but the medical journal ecosystem has […]

๐—ช๐—ฒ ๐—ฎ๐—น๐—ฟ๐—ฒ๐—ฎ๐—ฑ๐˜† ๐—ธ๐—ป๐—ผ๐˜„ ๐—บ๐—ถ๐—ฐ๐—ฟ๐—ผ๐—ฝ๐—น๐—ฎ๐˜€๐˜๐—ถ๐—ฐ๐˜€ ๐—ฎ๐—ฟ๐—ฒ ๐—ถ๐—ป ๐—ผ๐˜‚๐—ฟ ๐˜„๐—ฎ๐˜๐—ฒ๐—ฟ, ๐—ผ๐˜‚๐—ฟ ๐—ณ๐—ผ๐—ผ๐—ฑ, ๐—ฎ๐—ป๐—ฑ ๐—ผ๐˜‚๐—ฟ ๐—ผ๐—ฐ๐—ฒ๐—ฎ๐—ป๐˜€. ๐—•๐˜‚๐˜ ๐˜„๐—ต๐—ฎ๐˜ ๐—ต๐—ฎ๐—ฝ๐—ฝ๐—ฒ๐—ป๐˜€ ๐˜„๐—ต๐—ฒ๐—ป ๐˜๐—ต๐—ฒ๐˜† ๐—ฟ๐—ฒ๐—ฎ๐—ฐ๐—ต ๐˜๐—ต๐—ฒ ๐—ต๐˜‚๐—บ๐—ฎ๐—ป ๐—ฏ๐—ฟ๐—ฎ๐—ถ๐—ป?

๐—•๐—ฒ๐˜€๐˜ ๐—ณ๐—ผ๐—ฟ: ๐—›๐—ถ๐—ด๐—ต ๐—ฒ๐—ป๐—ด๐—ฎ๐—ด๐—ฒ๐—บ๐—ฒ๐—ป๐˜ ๐—ฎ๐—ป๐—ฑ ๐˜€๐—ต๐—ฎ๐—ฟ๐—ฒ๐—ฎ๐—ฏ๐—ถ๐—น๐—ถ๐˜๐˜†. ๐—œ๐˜ ๐—ฐ๐—ผ๐—ป๐—ป๐—ฒ๐—ฐ๐˜๐˜€ ๐—ฎ ๐—ฑ๐—ฒ๐—ฒ๐—ฝ๐—น๐˜† ๐˜๐—ฒ๐—ฐ๐—ต๐—ป๐—ถ๐—ฐ๐—ฎ๐—น ๐—ฝ๐—ฎ๐—ฝ๐—ฒ๐—ฟ ๐˜๐—ผ ๐—ฎ ๐—บ๐—ฎ๐˜€๐˜€๐—ถ๐˜ƒ๐—ฒ, ๐—ฟ๐—ฒ๐—ฎ๐—น-๐˜„๐—ผ๐—ฟ๐—น๐—ฑ ๐—ถ๐˜€๐˜€๐˜‚๐—ฒ ๐˜๐—ต๐—ฎ๐˜ ๐—ฒ๐˜ƒ๐—ฒ๐—ฟ๐˜† ๐—ฝ๐—ฟ๐—ผ๐—ณ๐—ฒ๐˜€๐˜€๐—ถ๐—ผ๐—ป๐—ฎ๐—น ๐—ผ๐—ป ๐—Ÿ๐—ถ๐—ป๐—ธ๐—ฒ๐—ฑ๐—œ๐—ป ๐—ฐ๐—ฎ๐—ป ๐—ฟ๐—ฒ๐—น๐—ฎ๐˜๐—ฒ ๐˜๐—ผ: ๐—ฝ๐—น๐—ฎ๐˜€๐˜๐—ถ๐—ฐ ๐—ฝ๐—ผ๐—น๐—น๐˜‚๐˜๐—ถ๐—ผ๐—ป ๐—ฎ๐—ป๐—ฑ ๐—ต๐˜‚๐—บ๐—ฎ๐—ป ๐—ต๐—ฒ๐—ฎ๐—น๐˜๐—ต. ๐—ช๐—ฒ ๐—ฎ๐—ฟ๐—ฒ ๐—น๐—ถ๐˜ƒ๐—ถ๐—ป๐—ด ๐—ถ๐—ป ๐˜๐—ต๐—ฒ “๐—ฃ๐—น๐—ฎ๐˜€๐˜๐—ถ๐—ฐ๐—ฒ๐—ป๐—ฒ” ๐—ฒ๐—ฟ๐—ฎโ€”๐—ฎ๐—ป๐—ฑ ๐—ถ๐˜ ๐—บ๐—ถ๐—ด๐—ต๐˜ ๐—ฏ๐—ฒ ๐—ฎ๐—น๐˜๐—ฒ๐—ฟ๐—ถ๐—ป๐—ด ๐—ต๐—ผ๐˜„ ๐˜„๐—ฒ ๐˜๐—ต๐—ถ๐—ป๐—ธ ๐—ฎ๐—ฏ๐—ผ๐˜‚๐˜ ๐—ฏ๐—ฟ๐—ฎ๐—ถ๐—ป ๐—ต๐—ฒ๐—ฎ๐—น๐˜๐—ต. ๐—ช๐—ฒ ๐—ฎ๐—น๐—ฟ๐—ฒ๐—ฎ๐—ฑ๐˜† ๐—ธ๐—ป๐—ผ๐˜„ ๐—บ๐—ถ๐—ฐ๐—ฟ๐—ผ๐—ฝ๐—น๐—ฎ๐˜€๐˜๐—ถ๐—ฐ๐˜€ ๐—ฎ๐—ฟ๐—ฒ ๐—ถ๐—ป ๐—ผ๐˜‚๐—ฟ ๐˜„๐—ฎ๐˜๐—ฒ๐—ฟ, […]

“๐—œ๐—ป๐˜€๐—ฎ๐—ป๐—ถ๐˜๐˜† ๐—ถ๐˜€ ๐—ฑ๐—ผ๐—ถ๐—ป๐—ด ๐˜๐—ต๐—ฒ ๐˜€๐—ฎ๐—บ๐—ฒ ๐˜๐—ต๐—ถ๐—ป๐—ด ๐—ผ๐˜ƒ๐—ฒ๐—ฟ ๐—ฎ๐—ป๐—ฑ ๐—ผ๐˜ƒ๐—ฒ๐—ฟ ๐—ฎ๐—ด๐—ฎ๐—ถ๐—ป ๐—ฎ๐—ป๐—ฑ ๐—ฒ๐˜…๐—ฝ๐—ฒ๐—ฐ๐˜๐—ถ๐—ป๐—ด ๐—ฑ๐—ถ๐—ณ๐—ณ๐—ฒ๐—ฟ๐—ฒ๐—ป๐˜ ๐—ฟ๐—ฒ๐˜€๐˜‚๐—น๐˜๐˜€.” Alzheimer’s disease research!

“๐—œ๐—ป๐˜€๐—ฎ๐—ป๐—ถ๐˜๐˜† ๐—ถ๐˜€ ๐—ฑ๐—ผ๐—ถ๐—ป๐—ด ๐˜๐—ต๐—ฒ ๐˜€๐—ฎ๐—บ๐—ฒ ๐˜๐—ต๐—ถ๐—ป๐—ด ๐—ผ๐˜ƒ๐—ฒ๐—ฟ ๐—ฎ๐—ป๐—ฑ ๐—ผ๐˜ƒ๐—ฒ๐—ฟ ๐—ฎ๐—ด๐—ฎ๐—ถ๐—ป ๐—ฎ๐—ป๐—ฑ ๐—ฒ๐˜…๐—ฝ๐—ฒ๐—ฐ๐˜๐—ถ๐—ป๐—ด ๐—ฑ๐—ถ๐—ณ๐—ณ๐—ฒ๐—ฟ๐—ฒ๐—ป๐˜ ๐—ฟ๐—ฒ๐˜€๐˜‚๐—น๐˜๐˜€.” ๐—™๐—ผ๐—ฟ ๐—ฑ๐—ฒ๐—ฐ๐—ฎ๐—ฑ๐—ฒ๐˜€, ๐˜๐—ต๐—ฒ ๐—ฏ๐—ถ๐—ผ๐˜๐—ฒ๐—ฐ๐—ต ๐—ถ๐—ป๐—ฑ๐˜‚๐˜€๐˜๐—ฟ๐˜† ๐—ต๐—ฎ๐˜€ ๐—ฝ๐—ผ๐˜‚๐—ฟ๐—ฒ๐—ฑ ๐—ฏ๐—ถ๐—น๐—น๐—ถ๐—ผ๐—ป๐˜€ ๐—ถ๐—ป๐˜๐—ผ ๐—ฎ ๐˜€๐—ถ๐—ป๐—ด๐˜‚๐—น๐—ฎ๐—ฟ ๐—ด๐—ผ๐—ฎ๐—น ๐—ณ๐—ผ๐—ฟ ๐—”๐—น๐˜‡๐—ต๐—ฒ๐—ถ๐—บ๐—ฒ๐—ฟโ€™๐˜€ ๐—ฑ๐—ถ๐˜€๐—ฒ๐—ฎ๐˜€๐—ฒ: ๐—ฐ๐—น๐—ฒ๐—ฎ๐—ฟ๐—ถ๐—ป๐—ด ๐—ฎ๐—บ๐˜†๐—น๐—ผ๐—ถ๐—ฑ ๐—ฝ๐—น๐—ฎ๐—พ๐˜‚๐—ฒ๐˜€ ๐—ฎ๐—ป๐—ฑ ๐˜๐—ฎ๐˜‚ ๐˜๐—ฎ๐—ป๐—ด๐—น๐—ฒ๐˜€ ๐—ณ๐—ฟ๐—ผ๐—บ ๐˜๐—ต๐—ฒ ๐—ฏ๐—ฟ๐—ฎ๐—ถ๐—ป. ๐—ฌ๐—ฒ๐˜, ๐—ฐ๐—น๐—ถ๐—ป๐—ถ๐—ฐ๐—ฎ๐—น ๐˜๐—ฟ๐—ถ๐—ฎ๐—น ๐—ฎ๐—ณ๐˜๐—ฒ๐—ฟ ๐—ฐ๐—น๐—ถ๐—ป๐—ถ๐—ฐ๐—ฎ๐—น ๐˜๐—ฟ๐—ถ๐—ฎ๐—น ๐—ต๐—ฎ๐˜€ ๐—ณ๐—ฎ๐—ฐ๐—ฒ๐—ฑ ๐—ฑ๐—ถ๐˜€๐—ฎ๐—ฝ๐—ฝ๐—ผ๐—ถ๐—ป๐˜๐—ถ๐—ป๐—ด ๐—ณ๐—ฎ๐—ถ๐—น๐˜‚๐—ฟ๐—ฒ๐˜€. ๐—ง๐—ต๐—ฒ ๐—ฝ๐—น๐—ฎ๐—พ๐˜‚๐—ฒ๐˜€ ๐—ฎ๐—ฟ๐—ฒ ๐—ฟ๐—ฒ๐—บ๐—ผ๐˜ƒ๐—ฒ๐—ฑ, ๐—ฏ๐˜‚๐˜ ๐˜๐—ต๐—ฒ ๐—ฐ๐—ผ๐—ด๐—ป๐—ถ๐˜๐—ถ๐˜ƒ๐—ฒ […]

Alzheimer’s Dual Sequestration Hypothesis

๐๐ž๐ฐ ๐๐ฎ๐›๐ฅ๐ข๐œ๐š๐ญ๐ข๐จ๐ง ๐ข๐ง ๐…๐ซ๐ž๐ž ๐๐ž๐ฎ๐ซ๐จ๐ฉ๐š๐ญ๐ก๐จ๐ฅ๐จ๐ ๐ฒ (๐‰๐ฎ๐ง๐ž ๐Ÿ๐ŸŽ๐Ÿ๐Ÿ”) ๐ˆ ๐š๐ฆ ๐ฉ๐ฅ๐ž๐š๐ฌ๐ž๐ ๐ญ๐จ ๐ฌ๐ก๐š๐ซ๐ž ๐จ๐ฎ๐ซ ๐ฅ๐š๐ญ๐ž๐ฌ๐ญ ๐œ๐ฅ๐ข๐ง๐ข๐œ๐จ๐ฉ๐š๐ญ๐ก๐จ๐ฅ๐จ๐ ๐ข๐œ๐š๐ฅ ๐ฎ๐ฉ๐๐š๐ญ๐ž ๐š๐๐๐ซ๐ž๐ฌ๐ฌ๐ข๐ง๐  ๐š ๐ฉ๐ž๐ซ๐ฌ๐ข๐ฌ๐ญ๐ž๐ง๐ญ ๐ฉ๐š๐ซ๐š๐๐จ๐ฑ ๐ข๐ง ๐€๐ฅ๐ณ๐ก๐ž๐ข๐ฆ๐ž๐ซ’๐ฌ ๐๐ข๐ฌ๐ž๐š๐ฌ๐ž: ๐ฐ๐ก๐ฒ ๐ญ๐ก๐ž๐ซ๐š๐ฉ๐ข๐ž๐ฌ ๐ญ๐š๐ซ๐ ๐ž๐ญ๐ข๐ง๐  ๐ญ๐ก๐ž ๐ซ๐ž๐ฆ๐จ๐ฏ๐š๐ฅ ๐จ๐Ÿ ๐š๐ฆ๐ฒ๐ฅ๐จ๐ข๐-ฮฒ ๐ฉ๐ฅ๐š๐ช๐ฎ๐ž๐ฌ ๐š๐ง๐ ๐ญ๐š๐ฎ ๐ญ๐š๐ง๐ ๐ฅ๐ž๐ฌ ๐œ๐จ๐ง๐ฌ๐ข๐ฌ๐ญ๐ž๐ง๐ญ๐ฅ๐ฒ ๐ฌ๐ก๐จ๐ฐ ๐š ๐œ๐ซ๐ข๐ญ๐ข๐œ๐š๐ฅ ๐๐ข๐ฌ๐ฌ๐จ๐œ๐ข๐š๐ญ๐ข๐จ๐ง ๐Ÿ๐ซ๐จ๐ฆ ๐œ๐จ๐ซ๐ž ๐œ๐ฅ๐ข๐ง๐ข๐œ๐š๐ฅ ๐ฉ๐š๐ญ๐ก๐จ๐ ๐ž๐ง๐ž๐ฌ๐ข๐ฌ. ๐ˆ๐ง “๐€๐ฅ๐ณ๐ก๐ž๐ข๐ฆ๐ž๐ซ’๐ฌ ๐๐ข๐ฌ๐ž๐š๐ฌ๐ž ๐ข๐ง ๐ญ๐ก๐ž ๐๐ฅ๐š๐ฌ๐ญ๐ข๐œ๐ž๐ง๐ž ๐ž๐ซ๐š: ๐š ๐œ๐ฅ๐ข๐ง๐ข๐œ๐จ๐ฉ๐š๐ญ๐ก๐จ๐ฅ๐จ๐ ๐ข๐œ๐š๐ฅ ๐ฎ๐ฉ๐๐š๐ญ๐ž ๐จ๐ง ๐ญ๐ก๐ž […]

Book Review by Michael A. S. Guth: Outlaw (Battle Born #2) by Jack Stewart

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Diffuse Lewy Body Dementia in the Great Robin Williams

I have the deepest, most profound respect for Robin Williams. I wish it were more widely known, while he was still living, what a decent, caring, sympathetic person Robin Williams was. I just finished watching the documentary โ€œRobinโ€™s Wishโ€ (available to stream on Plex and Tubi) and learned that the cause of death in the […]