Abstract Nicotinamide riboside (NR), a precursor to nicotinamide adenine dinucleotide (NAD+), has emerged as a popular anti-aging supplement due to its role in cellular energy metabolism and sirtuin activation. Preclinical studies in model organisms demonstrate that NR supplementation can counteract age-related NAD+ decline, improving mitochondrial function, reducing inflammation, and extending lifespan. However, human clinical trials […]

Researchers are pioneering a promising new frontier in cancer treatment with dendritic cell (DC) immunotherapy for glioblastoma, one of the most aggressive and treatment-resistant brain cancers. Despite decades of research, glioblastoma remains a critical unmet medical need, with limited therapeutic options and poor survival rates. DC immunotherapy offers a novel approach by harnessing the patient’s […]

The field of nuclear medicine is undergoing a transformative shift, driven by advances in radiopharmaceuticals—a powerful class of targeted drugs that combine radioactive isotopes with biological molecules to diagnose and treat cancer with unprecedented precision. With innovations in PET imaging and therapeutic radioligands, these tools are reshaping oncology by enabling earlier detection, personalized treatment, and […]

𝐄𝐯𝐞𝐫𝐲 𝐬𝐚𝐯𝐯𝐲 𝐢𝐧𝐝𝐢𝐯𝐢𝐝𝐮𝐚𝐥 𝐤𝐧𝐨𝐰𝐬 𝐭𝐡𝐞 𝐬𝐞𝐜𝐫𝐞𝐭 𝐭𝐨 𝐞𝐧𝐡𝐚𝐧𝐜𝐢𝐧𝐠 𝐭𝐡𝐞𝐢𝐫 𝐰𝐞𝐥𝐥-𝐛𝐞𝐢𝐧𝐠: 𝐭𝐡𝐞𝐲 𝐚𝐥𝐥 𝐭𝐚𝐤𝐞 𝐬𝐮𝐩𝐩𝐥𝐞𝐦𝐞𝐧𝐭𝐬! 𝐈𝐭’𝐬 𝐚 𝐮𝐧𝐢𝐯𝐞𝐫𝐬𝐚𝐥 𝐭𝐫𝐮𝐭𝐡—𝐭𝐡𝐨𝐬𝐞 𝐰𝐡𝐨 𝐯𝐚𝐥𝐮𝐞 𝐭𝐡𝐞𝐢𝐫 𝐡𝐞𝐚𝐥𝐭𝐡 𝐚𝐧𝐝 𝐢𝐧𝐭𝐞𝐥𝐥𝐢𝐠𝐞𝐧𝐜𝐞 𝐚𝐫𝐞 𝐨𝐧 𝐛𝐨𝐚𝐫𝐝 𝐰𝐢𝐭𝐡 𝐭𝐡𝐢𝐬 𝐞𝐬𝐬𝐞𝐧𝐭𝐢𝐚𝐥 𝐩𝐫𝐚𝐜𝐭𝐢𝐜𝐞! As of 2022, ~37% of U.S. adults reported using at least one complementary or integrative health approach (e.g., supplements, chiropractic care, yoga, meditation). If you’re asking specifically about dietary […]

“It’s my goal to live to 100 – and it’s not just diet and exercise that will help me achieve it.” — Devi Sridhar Let’s break down the science-backed habits and principles that Devi Sridhar likely incorporates (or advocates for) in her quest to live to 100, beyond just diet and exercise. Many of these […]

Next-Generation Food Fortification: Advances in Nanoencapsulation, Biofortification, and 3D-Printed Functional Foods for Precision Nutrition  Introduction  Context: Global malnutrition challenges and limitations of conventional fortification. Opportunity: Role of novel technologies in addressing bioavailability, sustainability, and personalization. Objective: Review cutting-edge techniques (nanoencapsulation, biofortification, 3D printing) and their synergies for precision nutrition. Global Nutrition Gap: 2 billion people […]

The Many Roads to Healing: How You Can Join the Fight Against Cancer Everyone knows someone. A friend, a parent, a coworker, maybe even yourself—cancer doesn’t care about the boundaries we set. It shows up uninvited, flips life upside down, and forces people into battles they never imagined they’d fight. But here’s the truth that […]

Image by Freepik Shake the Dust Off: Seven Ways to Take Charge of Your Health by Gabriel Patel You don’t need a personal trainer, a weeklong juice cleanse, or a stack of wellness books to start steering your own ship. Health isn’t a finish line, it’s the day-in-day-out. It’s the choices you make between the […]

Mitochondrial dysfunction is a key aspect of aging, impacting health and contributing to various age-related diseases. ​ https://urfjournals.org/open-access/mitochondrial-dysfunction-a-hallmark-of-aging-mechanisms-consequences-and-therapeutic-strategies.pdf 1. Introduction Mitochondria are essential for energy production and cellular homeostasis. ​ Aging leads to mitochondrial dysfunction, affecting cellular and systemic health. ​ Mitochondrial dysfunction is linked to neurodegenerative diseases, metabolic disorders, and cardiovascular issues. ​ 2. […]

1. Mechanisms of Stem Cell Exhaustion Telomere Attrition and Replicative Senescence: Studies have shown that telomere shortening in stem cells limits their replicative capacity, leading to senescence or apoptosis. For example, hematopoietic stem cells (HSCs) with critically short telomeres exhibit reduced self-renewal and differentiation potential (Ju et al., Cell Stem Cell, 2007). Telomerase activation has been […]