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subsequent research has shown that all people need some breakdown of acetylcholine in their brains while sleeping to reach the deeper, more restful stages of sleep. Therefore, medical scientists now say that Aricept and other AChEIs should be taken in the morning, not at bedtime. Contrary to news articles you may read, AChEIs are useful in the advanced stages of the disease, not just in the early stages. Even advanced-stage patients need as much acetylcholine as they can get. Some clinical studies are now underway to see whether the long-term, chronic consumption of AChEIs can slow the progression of Alzheimer’s disease, even if they cannot stop the pathology of the disease.
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